New: OSPS Version 12 → PBPK-QSP Modeling with MoBiĀ®

Formula Types (M02-12)


Description
You will learn to apply different equation types (Explicit, Sum, Conditional). We will exemplarily assume a simplified circadian clearance of the antiviral medication aciclovir.
Content
  • Info: Course Goal
  • Introduction
  • Info: Equations in the OSPS
  • Start with the Aciclovir PBPK Model
  • Explicit and Differential Equation
  • Time-Dependent Formula: Circadian Rhythm
  • Differential Equation: Daytime-Dependent Clearance
  • Simulation: With Circadian Clearance
  • Simulation: Without Circadian Clearance
  • Catch-Up Point 1
  • Sum and Conditional Equation
  • Sum Formula: Total Aciclovir Amount
  • Conditional Equation: Relative Aciclovir Amount
  • Simulation: Amount of Aciclovir
  • Final Overview
  • The End
  • Learning Outcome
  • Brief Course Evaluation
Completion rules
  • All units must be completed
  • Leads to a certificate with a duration: Forever