Female Reproductive Tract (M05-12)

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New: OSPS Version 12 → PBPK-QSP Modeling with MoBi®

Female Reproductive Tract (M05-12)

Description

Content

Info: Course Goal
PBPK Model of a Female in PK-Sim®
Info: Metronidazole
Expression Profiles: CYP2A6 & CYP3A4
Individual: Woman
Compound: Metronidazole
Administration Protocol: Metronidazole IV 500 mg
Simulation: Metronidazole IV 500 mg (20 min)
Catch-Up Point 1
Export the Simulation from PK-Sim to MoBi®
PBPK model extension for FRT in MoBi®
Info: Female Reproductive Tract (FRT)
Info: PBPK Model Structure of the Female Reproductive Tract
Extension Module: Female Reproductive Tract
Parameter Values: Diffusion Coefficient & Fraction Unionized
Initial Conditions: Female Reproductive Tract
Observed Data: Female Reproductive Tract
Simulation: Female Reproductive Tract
Catch-Up Point 2
Local administration in the FRT in MoBi®
Info: Female Reproductive Tract Administration Routes
Extension Module: Cervicovaginal Administration
Parameter Values: Zero Order Process
Observed Data: Cervicovaginal Administration
Simulation: Cervicovaginal Administration
Final Overview
The End
Brief Course Evaluation

Completion rules

All units must be completed
Leads to a certificate with a duration: Forever

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